HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: SH3B4 (Q9P0V3)
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)
Gene: SH3BP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

Property	Details
Experiments	33761321, 33961781, 35271311, 36931259, 20936779, 15324660, 17353931, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid pooling approach, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 963
+	Hs
		972080 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		1049851 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		972300 1433E_MOUSE (1-244): 2.03e-141: 398: 63.53		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		967122 1433G_MOUSE (1-247): 3.17e-139: 392: 100.00		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		999181 1433F_MOUSE (1-246): 1.52e-136: 385: 86.99		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		730304 1433B_HUMAN (2-247): 1.92e-109: 317: 75.40		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		990811 1433Z_HUMAN (2-245): 2.4e-108: 314: 74.59		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Hs
		691493 1433T_HUMAN (2-245): 5.55e-105: 305: 70.33		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		1362880 1433B_MOUSE (2-247): 8.61e-109: 315: 75.81		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		990036 1433Z_MOUSE (2-245): 8.5e-109: 315: 74.59		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		730928 1433S_HUMAN (2-245): 1.87e-98: 289: 65.16		SH3B4_HUMAN (1-963): 0: 1835: 100.00
+	Mm
		996628 1433T_MOUSE (2-245): 3.01e-105: 306: 70.73		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Mm
		267039 1433S_MOUSE (2-236): 1.39e-95: 281: 65.96		SH3B4_MOUSE (1-963): 0: 1813: 91.60
+	Hs
		971676 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		MACC1_HUMAN (140-958): 0: 1340: 43.71