HitPredict

Interactor 1: CD82 (P27701)
CD82 antigen (C33 antigen) (IA4) (Inducible membrane protein R2) (Metastasis suppressor Kangai-1) (Suppressor of tumorigenicity 6 protein) (Tetraspanin-27) (Tspan-27) (CD antigen CD82)
Gene: CD82

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9862348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 267 Hs			1 236
+	Hs
		948746 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		CD81_HUMAN (1-236): 1.96e-63: 199: 100.00
+	Hs
		697351 CD82_HUMAN (1-267): 1.33e-72: 224: 100.00		CD151_HUMAN (3-231): 3.49e-55: 178: 25.40
+	Hs
		641915 CD82_HUMAN (1-267): 1.33e-72: 224: 100.00		CD9_HUMAN (1-234): 7.49e-54: 174: 43.59
+	Hs
		948883 TSN14_HUMAN (10-258): 1.21e-62: 199: 23.14		CD81_HUMAN (1-236): 1.96e-63: 199: 100.00
+	Hs
		477405 CD82_HUMAN (1-267): 1.33e-72: 224: 100.00		CD63_HUMAN (1-232): 1.05e-52: 172: 22.95
+	Hs
		873766 CD151_HUMAN (3-261): 4.96e-58: 187: 27.48		CD81_HUMAN (1-236): 1.96e-63: 199: 100.00
+	Hs
		873767 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		CD151_HUMAN (3-231): 3.49e-55: 178: 25.40
+	Hs
		622031 CD82_HUMAN (1-267): 1.33e-72: 224: 100.00		CD53_HUMAN (1-234): 1.33e-47: 158: 29.06
+	Hs
		641933 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		CD9_HUMAN (1-234): 7.49e-54: 174: 43.59
+	Hs
		967327 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		TSN14_HUMAN (11-230): 8.62e-53: 173: 21.65
+	Hs
		298987 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		TSN9_HUMAN (5-233): 5.16e-53: 172: 26.05
+	Hs
		873784 TSN14_HUMAN (10-258): 1.21e-62: 199: 23.14		CD151_HUMAN (3-231): 3.49e-55: 178: 25.40
+	Hs
		641966 TSN14_HUMAN (10-258): 1.21e-62: 199: 23.14		CD9_HUMAN (1-234): 7.49e-54: 174: 43.59
+	Hs
		641923 CD151_HUMAN (3-261): 4.96e-58: 187: 27.48		CD9_HUMAN (1-234): 7.49e-54: 174: 43.59
+	Hs
		349402 TSN5_HUMAN (8-267): 6.25e-65: 205: 27.07		TSN15_HUMAN (10-230): 2.63e-44: 152: 15.48
+	Hs
		349494 TSN14_HUMAN (10-258): 1.21e-62: 199: 23.14		TSN15_HUMAN (10-230): 2.63e-44: 152: 15.48
+	Hs
		349393 CD151_HUMAN (3-261): 4.96e-58: 187: 27.48		TSN15_HUMAN (10-230): 2.63e-44: 152: 15.48
+	Hs
		252587 CD151_HUMAN (3-261): 4.96e-58: 187: 27.48		TSN2_HUMAN (3-234): 5.39e-44: 149: 39.22