HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: TSN14 (Q8NG11)
Tetraspanin-14 (Tspan-14) (DC-TM4F2) (Transmembrane 4 superfamily member 14)
Gene: TSPAN14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32900848
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0072659 - protein localization to plasma membrane GO:0097197 - tetraspanin-enriched microdomain
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 270
+	Hs
		948746 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		TSN5_HUMAN (1-268): 2.97e-84: 254: 57.84
+	Hs
		967327 TSN5_HUMAN (6-235): 1.55e-55: 180: 21.59		TSN14_HUMAN (1-270): 3.51e-85: 257: 100.00
+	Hs
		349401 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		TSN15_HUMAN (5-268): 3.36e-61: 196: 31.82
+	Hs
		697352 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		CD82_HUMAN (9-264): 3.06e-58: 188: 22.43
+	Hs
		222340 TSN6_HUMAN (1-234): 1.27e-57: 184: 22.13		TSN15_HUMAN (5-268): 3.36e-61: 196: 31.82
+	Hs
		349402 TSN5_HUMAN (6-235): 1.55e-55: 180: 21.59		TSN15_HUMAN (5-268): 3.36e-61: 196: 31.82
+	Hs
		349393 CD151_HUMAN (3-231): 3.49e-55: 178: 25.40		TSN15_HUMAN (5-268): 3.36e-61: 196: 31.82
+	Hs
		873766 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		CD151_HUMAN (7-262): 2.99e-53: 175: 23.94
+	Hs
		697351 CD151_HUMAN (3-231): 3.49e-55: 178: 25.40		CD82_HUMAN (9-264): 3.06e-58: 188: 22.43
+	Hs
		948736 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		CD81_HUMAN (6-264): 2.96e-50: 166: 22.10
+	Hs
		165170 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		TSN4_HUMAN (15-261): 2.3e-49: 164: 26.10
+	Hs
		641932 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		CD9_HUMAN (6-265): 5.78e-47: 158: 23.49
+	Hs
		117205 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		K4DIA7_HUMAN (7-243): 2.62e-46: 156: 24.17
+	Hs
		873767 TSN5_HUMAN (6-235): 1.55e-55: 180: 21.59		CD151_HUMAN (7-262): 2.99e-53: 175: 23.94
+	Hs
		298987 TSN5_HUMAN (6-235): 1.55e-55: 180: 21.59		TSN9_HUMAN (9-268): 4.36e-53: 174: 24.05
+	Hs
		622040 CD81_HUMAN (1-236): 1.96e-63: 199: 100.00		CD53_HUMAN (15-263): 1.05e-45: 154: 22.09
+	Hs
		641933 TSN5_HUMAN (6-235): 1.55e-55: 180: 21.59		CD9_HUMAN (6-265): 5.78e-47: 158: 23.49
+	Hs
		641923 CD151_HUMAN (3-231): 3.49e-55: 178: 25.40		CD9_HUMAN (6-265): 5.78e-47: 158: 23.49
+	Hs
		252587 CD151_HUMAN (3-231): 3.49e-55: 178: 25.40		TSN2_HUMAN (16-160): 5.52e-14: 70.9: 31.08