HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: PTN4 (P29074)
Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (MEG) (PTPase-MEG1)
Gene: PTPN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~Y_phosphatase
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 926
+	Hs
		699599 P85A_HUMAN (1-724): 0: 590: 100.00		PTN6_HUMAN (546-913): 7.17e-135: 418: 32.46
+	Hs
		614654 P85A_HUMAN (1-724): 0: 590: 100.00		PTPRA_HUMAN (639-912): 1.1e-96: 323: 33.45
+	Hs
		699756 P85A_HUMAN (1-724): 0: 590: 100.00		PTPRK_HUMAN (643-914): 3.12e-56: 213: 28.07
+	Hs
		269546 SRGP2_HUMAN (118-668): 6.27e-59: 217: 13.38		PTN13_HUMAN (618-912): 7.12e-104: 358: 35.02
+	Hs
		1090140 RHG29_HUMAN (102-637): 1.75e-52: 199: 12.88		PTN13_HUMAN (618-912): 7.12e-104: 358: 35.02
+	Hs
		320532 CHIN_HUMAN (580-696): 2.15e-12: 71.9: 16.81		FARP2_HUMAN (8-507): 5.45e-134: 429: 34.40
+	Hs
		67670 RHG32_HUMAN (14-356): 8.12e-56: 209: 17.71		PTPRK_HUMAN (643-914): 3.12e-56: 213: 28.07
+	Hs
		269556 SRGP2_HUMAN (118-668): 6.27e-59: 217: 13.38		PTN14_HUMAN (30-319): 6.03e-30: 130: 31.00