HitPredict

Interactor 1: PSB8 (P28062)
Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein)
Gene: PSMB8

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 276 Hs			1 329
+	Hs
		1404137 PSB7_HUMAN (70-264): 3.59e-83: 252: 26.15		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		701253 PSB5_HUMAN (1-272): 1.37e-82: 250: 58.46		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		700768 PSA5_HUMAN (49-271): 3.94e-82: 248: 16.81		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		681750 PSA4_HUMAN (47-268): 1.16e-79: 243: 16.88		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		681248 PSA2_HUMAN (49-272): 1.06e-79: 242: 19.74		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		701100 PSB6_HUMAN (52-255): 5.84e-80: 242: 31.22		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Hs
		954936 PSA6_HUMAN (43-275): 8.2e-80: 242: 13.31		UCHL5_HUMAN (1-329): 8.38e-175: 489: 100.00
+	Sp
		1462954 PSA5_SCHPO (49-274): 4.05e-84: 253: 16.53		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		1068363 PSA3_SCHPO (47-276): 1.43e-82: 250: 15.04		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Sp
		207228 PSB1_SCHPO (56-258): 2.91e-80: 243: 31.86		UBLH2_SCHPO (7-325): 3.8e-114: 334: 38.77
+	Dm
		762550 Q7K148_DROME (1-274): 2.07e-84: 255: 48.92		UCHL_DROME (8-228): 1.94e-79: 243: 24.78
+	Dm
		762574 PSA5_DROME (49-272): 4.15e-81: 246: 18.67		UCHL_DROME (8-228): 1.94e-79: 243: 24.78
+	Hs
		488405 PSA4_HUMAN (47-268): 1.16e-79: 243: 16.88		UCHL1_HUMAN (10-226): 4.55e-75: 231: 22.22
+	Hs
		488437 PSA6_HUMAN (43-275): 8.2e-80: 242: 13.31		UCHL1_HUMAN (10-226): 4.55e-75: 231: 22.22
+	Hs
		1364535 PSB7_HUMAN (70-264): 3.59e-83: 252: 26.15		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		700698 PSA5_HUMAN (49-271): 3.94e-82: 248: 16.81		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		681693 PSA4_HUMAN (47-268): 1.16e-79: 243: 16.88		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		681207 PSA2_HUMAN (49-272): 1.06e-79: 242: 19.74		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		701063 PSB6_HUMAN (52-255): 5.84e-80: 242: 31.22		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29
+	Hs
		954869 PSA6_HUMAN (43-275): 8.2e-80: 242: 13.31		BAP1_HUMAN (246-315): 2.1e-16: 82: 34.29