HitPredict

Interactor 1: PSB4 (P28070)
Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3) (Proteasome subunit beta-7) (beta-7)
Gene: PSMB4

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PI31_Prot_C~Proteasome
Common GO terms	GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 264 Hs			1 271
+	Hs
		700697 PSA5_HUMAN (26-252): 1.18e-76: 234: 13.69		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		165385 PSA7_HUMAN (33-255): 9.95e-76: 232: 14.16		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		681206 PSA2_HUMAN (28-257): 2.21e-74: 228: 14.29		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		954868 PSA6_HUMAN (26-261): 4.86e-74: 227: 11.69		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		1363752 PSB7_HUMAN (51-253): 4.48e-70: 218: 18.23		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		633756 PSB1_HUMAN (26-246): 6.32e-70: 217: 22.61		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		954826 PSA6_HUMAN (26-261): 4.86e-74: 227: 11.69		Q5QPM9_HUMAN (1-183): 1.98e-104: 302: 100.00