HitPredict

Interactor 1: PSB6 (P28072)
Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) (Proteasome subunit beta-1) (beta-1)
Gene: PSMB6

Interactor 2: PSMA8 (Q8TAA3)
Proteasome subunit alpha-type 8 (Proteasome alpha 4 subunit) (Alpha4s) (Proteasome subunit alpha-type 7-like)
Gene: PSMA8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	17948026
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 239 Hs			1 256
+	Hs
		700692 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSMA8_HUMAN (1-238): 1.58e-105: 307: 100.00
+	Hs
		165267 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA7_HUMAN (5-238): 2.03e-101: 297: 82.91
+	Dm
		652742 Q7K148_DROME (31-218): 1.89e-87: 262: 30.69		PSA71_DROME (1-237): 1.72e-94: 279: 69.20
+	Dm
		47746 A0AQH0_DROME (25-237): 5.13e-87: 259: 57.28		PSA71_DROME (1-237): 1.72e-94: 279: 69.20
+	Dm
		1264669 Q7K148_DROME (31-218): 1.89e-87: 262: 30.69		PSA5_DROME (3-241): 9.26e-92: 272: 35.89
+	Dm
		652806 Q9VUJ1_DROME (37-219): 2.86e-84: 253: 28.96		PSA71_DROME (1-237): 1.72e-94: 279: 69.20
+	Sp
		721233 PSB5_SCHPO (13-218): 6.8e-87: 260: 26.54		PSA5_SCHPO (3-245): 1.13e-91: 272: 35.46
+	Dm
		47775 A0AQH0_DROME (25-237): 5.13e-87: 259: 57.28		PSA5_DROME (3-241): 9.26e-92: 272: 35.89
+	Sp
		721231 PSB5_SCHPO (13-218): 6.8e-87: 260: 26.54		PSA4_SCHPO (3-255): 6.95e-91: 270: 53.33
+	Sp
		1082946 PSA5_SCHPO (3-230): 1.19e-85: 256: 20.75		PSA4_SCHPO (3-255): 6.95e-91: 270: 53.33
+	Dm
		1376942 Q9VUJ1_DROME (37-219): 2.86e-84: 253: 28.96		PSA5_DROME (3-241): 9.26e-92: 272: 35.89
+	Hs
		700596 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA6_HUMAN (2-243): 1.55e-91: 272: 29.27
+	Hs
		700556 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA5_HUMAN (3-240): 2.24e-91: 271: 36.74
+	Hs
		680778 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA1_HUMAN (3-249): 1.11e-89: 267: 31.08
+	Ss
		99238 F2Z5K2_PIG (3-230): 1.87e-84: 253: 18.75		F2Z5L7_PIG (3-249): 1.11e-89: 267: 31.08
+	Hs
		681576 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA4_HUMAN (1-237): 2.55e-89: 266: 34.84
+	Dm
		821841 Q7K148_DROME (31-218): 1.89e-87: 262: 30.69		PSA2_DROME (4-222): 1.8e-47: 159: 40.27
+	Dm
		47749 A0AQH0_DROME (25-237): 5.13e-87: 259: 57.28		PSA2_DROME (4-222): 1.8e-47: 159: 40.27
+	Dm
		821936 Q9VUJ1_DROME (37-219): 2.86e-84: 253: 28.96		PSA2_DROME (4-222): 1.8e-47: 159: 40.27
+	Hs
		681107 PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75		PSA2_HUMAN (1-240): 6.61e-46: 155: 39.51