HitPredict

Interactor 1: PSB5 (P28074)
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X) (Proteasome subunit beta-5) (beta-5)
Gene: PSMB5

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35358511, 27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Hs			1 399
+	Hs
		700659 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		DDI2_HUMAN (1-399): 1.68e-162: 463: 100.00
+	Hs
		1216195 PSB7_HUMAN (39-251): 7.53e-82: 248: 25.82		DDI2_HUMAN (1-399): 1.68e-162: 463: 100.00
+	Hs
		701197 PSB5_HUMAN (1-263): 1.08e-92: 275: 100.00		DDI1_HUMAN (1-392): 7.47e-148: 426: 70.75
+	Hs
		700696 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		DDI1_HUMAN (1-392): 7.47e-148: 426: 70.75
+	Hs
		1356067 PSB7_HUMAN (39-251): 7.53e-82: 248: 25.82		DDI1_HUMAN (1-392): 7.47e-148: 426: 70.75
+	Hs
		701244 PSB5_HUMAN (1-263): 1.08e-92: 275: 100.00		UBQL1_HUMAN (5-241): 5.8e-49: 176: 14.80
+	Hs
		701240 PSB5_HUMAN (1-263): 1.08e-92: 275: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		701234 PSB5_HUMAN (1-263): 1.08e-92: 275: 100.00		UBQL4_HUMAN (8-241): 1.81e-44: 164: 14.59
+	Hs
		700757 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		UBQL1_HUMAN (5-241): 5.8e-49: 176: 14.80
+	Hs
		700747 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1404130 PSB7_HUMAN (39-251): 7.53e-82: 248: 25.82		UBQL1_HUMAN (5-241): 5.8e-49: 176: 14.80
+	Hs
		1404124 PSB7_HUMAN (39-251): 7.53e-82: 248: 25.82		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		700743 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		UBQL4_HUMAN (8-241): 1.81e-44: 164: 14.59
+	Dm
		1264752 Q7K148_DROME (1-260): 4.62e-84: 254: 51.46		Q9VWD9_DROME (5-241): 9.03e-44: 161: 16.39
+	Dm
		1376946 PSA5_DROME (28-259): 1.94e-83: 251: 16.67		Q9VWD9_DROME (5-241): 9.03e-44: 161: 16.39
+	Dm
		1486769 Q9VUJ1_DROME (62-253): 2.43e-82: 249: 27.08		Q9VWD9_DROME (5-241): 9.03e-44: 161: 16.39
+	Hs
		701122 PSB5_HUMAN (1-263): 1.08e-92: 275: 100.00		RD23A_HUMAN (3-198): 2.37e-28: 116: 15.00
+	Hs
		700590 PSA5_HUMAN (28-258): 9.79e-86: 257: 15.64		RD23A_HUMAN (3-198): 2.37e-28: 116: 15.00
+	Sc
		735910 PSA5_YEAST (28-260): 1.35e-79: 242: 17.89		RAD23_YEAST (5-202): 3.9e-26: 110: 16.00
+	Sc
		721243 PSB5_YEAST (17-257): 8.12e-79: 241: 59.26		RAD23_YEAST (5-202): 3.9e-26: 110: 16.00