Interactor 1: IDH2 (P28241)
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)
Gene: IDH2
Interactor 2: LYS12 (P40495)
Homoisocitrate dehydrogenase, mitochondrial (HIcDH) (EC 1.1.1.87)
Gene: LYS12
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16429126 |
| Identification Methods | affinity chromatography technology, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Iso_dh~Iso_dh |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0005739 - mitochondrion GO:0051287 - NAD binding |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
