Protein: IDHP
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)

Gene: IDHP, IDH2
Organism: Homo sapiens
Interactions: 146
UniProt ID: P48735

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004450 - isocitrate dehydrogenase (NADP+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

822440

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

2

1

Small-scale

0.768

High

822520

KCMF1
E3 ubiquitin-protein ligase KCMF1

3

0

High-throughput

0.638

High

822518

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.602

High

496549

TAU
Microtubule-associated protein tau

2

2

High-throughput

0.601

High

226824

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

414818

CDK1
Cyclin-dependent kinase 1

1

3

Small-scale

0.561

High

822444

PLK1
Serine/threonine-protein kinase PLK1

1

2

Small-scale

0.561

High

822508

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.536

High

257948

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.513

High

362178

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

528761

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

536489

IRF2
Interferon regulatory factor 2

1

0

High-throughput

0.513

High

812957

CAZA2
F-actin-capping protein subunit alpha-2

1

0

High-throughput

0.513

High

822447

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.513

High

822465

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.513

High

822477

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

822487

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

822490

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

822493

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

822494

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

822513

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.513

High

822514

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

822515

ANLN
Anillin

1

0

High-throughput

0.513

High

822516

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

822529

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.513

High

822534

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

779006

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

380096

MAS
Proto-oncogene Mas

1

2

High-throughput

0.489

High

537724

INSRR
Insulin receptor-related protein

1

2

High-throughput

0.489

High

686613

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.489

High

822442

CEBPD
CCAAT/enhancer-binding protein delta

1

1

High-throughput

0.489

High

822480

KDM4D
Lysine-specific demethylase 4D

1

1

High-throughput

0.489

High

822489

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.489

High

822511

KDM4C
Lysine-specific demethylase 4C

1

1

High-throughput

0.489

High

822532

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

822528

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

440408

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

521800

CADH1
Cadherin-1

1

1

Small-scale

0.479

High

625221

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

654160

CALX
Calnexin

1

1

High-throughput

0.479

High

671750

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.479

High

739924

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.479

High

822446

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

2

High-throughput

0.479

High

822448

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

822451

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

822453

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

1

High-throughput

0.479

High

822454

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

822458

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

822460

CDC20
Cell division cycle protein 20 homolog

1

2

Small-scale

0.479

High

822462

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.479

High

822467

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

822475

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

2

Small-scale

0.479

High

822482

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

822485

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.479

High

822496

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

822503

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

822507

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.479

High

822517

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

2

Small-scale

0.479

High

822519

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

2

Small-scale

0.479

High

822521

CRNN
Cornulin

1

1

High-throughput

0.479

High

822522

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

822523

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

822525

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.479

High

417494

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.460

High

211530

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.458

High

242680

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

262752

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

298272

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

326508

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

417695

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

444863

ANXA5
Annexin A5

1

0

High-throughput

0.458

High

584900

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

713478

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

742126

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

822443

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

822445

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

822450

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

822464

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

822470

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

822471

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

822473

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

822481

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

822491

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

822492

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

822504

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

822509

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

822524

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

822526

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.458

High

822449

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

822476

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

822533

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

122255

RN103
E3 ubiquitin-protein ligase RNF103

1

1

High-throughput

0.437

High

242823

TRI13
E3 ubiquitin-protein ligase TRIM13

1

1

High-throughput

0.437

High

329491

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

338116

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.437

High

384473

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

552201

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

650640

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

719942

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

822452

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

822463

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

822469

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

822474

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

1

High-throughput

0.437

High

822484

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

822498

RN185
E3 ubiquitin-protein ligase RNF185

1

3

High-throughput

0.437

High

822505

RNF5
E3 ubiquitin-protein ligase RNF5

1

3

High-throughput

0.437

High

822512

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

973

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

822466

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

Small-scale

0.426

High

822479

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

822483

TMIG1
Transmembrane and immunoglobulin domain-containing protein 1

1

0

Small-scale

0.426

High

303671

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

706886

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.279

Low

725732

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

801590

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.279

Low

822455

HXC5
Homeobox protein Hox-C5

1

0

High-throughput

0.279

Low

822459

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.279

Low

822472

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

822488

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

822497

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

822499

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.279

Low

822502

TECTB
Beta-tectorin

1

0

High-throughput

0.279

Low

822506

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

822527

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

822530

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

822531

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.279

Low

62899

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.249

Low

100584

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

210457

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

0

High-throughput

0.249

Low

351985

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

379122

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.249

Low

428969

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.249

Low

441242

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.249

Low

822441

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

822461

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.249

Low

822468

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.249

Low

822478

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.249

Low

822486

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

822495

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

0

High-throughput

0.249

Low

822500

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

822501

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.249

Low

822510

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

401627

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

822456

E2F1
Transcription factor E2F1

1

0

High-throughput

0.232

Low

822457

TAGL
Transgelin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024