HitPredict

Interactor 1: GCYA2 (P33402)
Guanylate cyclase soluble subunit alpha-2 (GCS-alpha-2) (EC 4.6.1.2)
Gene: GUCY1A2

Interactor 2: SNTA1 (Q13424)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)
Gene: SNTA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.560

Property	Details
Experiments	15123239, 30126976
Identification Methods	unspecified method, peptide array, p8 filamentous phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 505
+	Hs
		704962 GCYA2_HUMAN (1-732): 0: 864: 100.00		SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62
+	Rn
		1144362 GCYA2_RAT (1-732): 0: 906: 90.98		DLG2_RAT (31-417): 3.19e-48: 180: 16.87
+	Hs
		704964 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG2_HUMAN (31-417): 8.33e-45: 170: 16.20
+	Rn
		677808 GCYA2_RAT (1-732): 0: 906: 90.98		DLG4_RAT (44-364): 7.6e-24: 107: 16.91
+	Rn
		1144082 GCYA2_RAT (1-732): 0: 906: 90.98		DLG3_RAT (47-345): 2.02e-23: 106: 16.77
+	Hs
		158263 GCYA2_HUMAN (1-732): 0: 864: 100.00		LIN7A_HUMAN (83-172): 5.01e-29: 116: 38.89
+	Hs
		704960 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG1_HUMAN (1-320): 1.18e-24: 110: 15.34
+	Hs
		704958 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG4_HUMAN (44-364): 8.62e-24: 107: 16.91
+	Hs
		704965 GCYA2_HUMAN (1-732): 0: 864: 100.00		DLG3_HUMAN (17-345): 3.57e-23: 105: 16.67
+	Hs
		158273 GCYB1_HUMAN (112-703): 0: 647: 33.87		LIN7A_HUMAN (83-172): 5.01e-29: 116: 38.89
+	Rn
		594291 GCYB1_RAT (112-703): 0: 646: 33.87		DLG4_RAT (44-364): 7.6e-24: 107: 16.91