Interactor 1: CXB2 (P29033)
Gap junction beta-2 protein (Connexin-26) (Cx26)
Gene: GJB2
Interactor 2: CXA5 (P36382)
Gap junction alpha-5 protein (Connexin-40) (Cx40)
Gene: GJA5
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.783 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Connexin~Connexin |
| Common GO terms | GO:0005886 - plasma membrane GO:0005921 - gap junction GO:0005922 - connexin complex GO:0007267 - cell-cell signaling GO:0016264 - gap junction assembly |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025