Interactor 1: CXB2 (P29033)
Gap junction beta-2 protein (Connexin-26) (Cx26)
Gene: GJB2
Interactor 2: CXA8 (P48165)
Gap junction alpha-8 protein (Connexin-50) (Cx50) (Lens fiber protein MP70)
Gene: GJA8
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.783 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Connexin~Connexin |
| Common GO terms | GO:0005243 - gap junction channel activity GO:0005886 - plasma membrane GO:0005922 - connexin complex GO:0007267 - cell-cell signaling GO:1990349 - gap junction-mediated intercellular transport |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
