HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.953

Property	Details
Experiments	25416956, 16189514, 32296183, 10951287, unassigned1304, 22394450
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach, x-ray crystallography
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	S_100~S_100
Common GO terms	GO:0005509 - calcium ion binding GO:0043542 - endothelial cell migration GO:0046914 - transition metal ion binding GO:0048306 - calcium-dependent protein binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 98
+	Hs
		1214472 Q5T7Y6_HUMAN (2-91): 3.16e-40: 131: 52.22		Q5T7Y6_HUMAN (2-91): 3.16e-40: 131: 52.22
+	Mm
		450157 S10A4_MOUSE (2-97): 3.81e-39: 127: 61.46		S10A4_MOUSE (2-97): 3.81e-39: 127: 61.46
+	Hs
		657022 S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00		S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22
+	Hs
		686780 S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00		S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46
+	Mm
		450158 S10A4_MOUSE (2-97): 3.81e-39: 127: 61.46		S10A1_MOUSE (2-91): 2.65e-37: 122: 51.11
+	Hs
		682510 Q5T7Y6_HUMAN (2-91): 3.16e-40: 131: 52.22		S100P_HUMAN (4-92): 1.21e-35: 118: 42.70
+	Hs
		657018 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22
+	Hs
		657021 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46
+	Hs
		686779 S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46		S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46
+	Hs
		706074 S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00		S10A3_HUMAN (2-98): 2.61e-36: 120: 43.30
+	Hs
		657024 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S10A3_HUMAN (2-98): 2.61e-36: 120: 43.30
+	Hs
		407637 Q5T7Y6_HUMAN (2-91): 3.16e-40: 131: 52.22		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		657019 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S100P_HUMAN (4-92): 1.21e-35: 118: 42.70
+	Hs
		407586 S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		657041 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S100Z_HUMAN (2-91): 3.93e-34: 114: 43.33
+	Hs
		407580 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		407583 S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46		S100B_HUMAN (4-92): 9.17e-33: 111: 44.94
+	Hs
		445129 S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46		S10A6_HUMAN (2-93): 2.21e-30: 104: 46.74