HitPredict

Interactor 1: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Interactor 2: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21888893
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 185
+	Hs
		1027018 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		420833 H2B1J_HUMAN (1-126): 8.38e-55: 169: 97.62		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		241519 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CBX3_HUMAN (1-177): 2.11e-63: 195: 69.49
+	Hs
		420825 H2B1J_HUMAN (1-126): 8.38e-55: 169: 97.62		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		949797 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX1_HUMAN (1-185): 2.21e-62: 193: 100.00
+	Hs
		800398 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		241469 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		800336 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		CBX5_HUMAN (1-183): 9.59e-60: 186: 57.45
+	Hs
		203602 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		SUV91_HUMAN (13-121): 4.22e-29: 112: 21.10
+	Hs
		1059155 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		1087494 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CDYL_HUMAN (7-120): 2.53e-25: 103: 25.86
+	Hs
		316041 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		315974 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CBX6_HUMAN (12-101): 1.25e-25: 103: 30.00
+	Hs
		707633 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CBX2_HUMAN (10-110): 2.55e-25: 103: 29.70
+	Hs
		123255 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		1087415 H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		123191 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		123222 H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62		CBX4_HUMAN (12-89): 1e-24: 101: 34.62
+	Hs
		241642 H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07
+	Hs
		707753 H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00		CBX8_HUMAN (12-88): 1.45e-24: 100: 35.07