Protein: LEU9
2-isopropylmalate synthase 2, mitochondrial (EC 2.3.3.13) (Alpha-IPM synthase 2) (Alpha-isopropylmalate synthase 2) (Alpha-isopropylmalate synthase II)

Gene: LEU9
Organism: Saccharomyces cerevisiae S288C
Interactions: 23
UniProt ID: Q12166

Gene Ontology (top 5):
GO:0003852 - 2-isopropylmalate synthase activity
GO:0005739 - mitochondrion
GO:0009098 - L-leucine biosynthetic process
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

439600

LEU1
2-isopropylmalate synthase

8

14

Small-scale

0.964

High

1084527

LEU9
2-isopropylmalate synthase 2, mitochondrial

2

14

High-throughput

0.762

High

1053101

RSA3
Ribosome assembly protein 3

1

1

High-throughput

0.489

High

510904

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

1040561

ESP1
Separin

1

1

High-throughput

0.479

High

554741

YPK1
Serine/threonine-protein kinase YPK1

1

2

High-throughput

0.470

High

531528

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

595011

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

1061400

LAM6
Membrane-anchored lipid-binding protein LAM6

1

0

Small-scale

0.458

High

752877

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.445

High

708511

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.437

High

748584

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.437

High

897522

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.437

High

1038119

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.437

High

1042268

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.437

High

805720

YHS2
MIP18 family protein YHR122W

1

1

High-throughput

0.417

High

525518

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.407

High

546709

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.407

High

810788

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.407

High

1056452

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.407

High

798467

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.265

Low

863781

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025