HitPredict

Interactor 1: PTN22 (P29352)
Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (PEST-domain phosphatase) (PEP)
Gene: Ptpn22

Interactor 2: PPIP1 (P97814)
Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1)
Gene: Pstpip1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9804817
Identification Methods	competition binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 802 Mm			1 415
+	Hs
		220821 PTN22_HUMAN (1-802): 0: 1068: 70.53		PPIP1_HUMAN (1-415): 1.06e-80: 256: 87.98
+	Mm
		711239 PTN22_MOUSE (1-802): 0: 1130: 100.00		PPIP2_MOUSE (2-324): 5.52e-54: 184: 41.98
+	Hs
		1436776 PTN22_HUMAN (1-802): 0: 1068: 70.53		PPIP2_HUMAN (2-324): 5.35e-54: 184: 42.90
+	Hs
		1154200 PTN22_HUMAN (1-802): 0: 1068: 70.53		ITSN1_HUMAN (339-414): 1.25e-09: 62.5: 21.05
+	Hs
		220765 PTN12_HUMAN (1-800): 0: 842: 34.49		PPIP1_HUMAN (1-415): 1.06e-80: 256: 87.98
+	Mm
		777185 PTN12_MOUSE (1-800): 0: 815: 35.03		PPIP1_MOUSE (1-415): 1.23e-81: 258: 100.00
+	Hs
		1050822 PTN12_HUMAN (1-800): 0: 842: 34.49		PPIP2_HUMAN (2-324): 5.35e-54: 184: 42.90
+	Mm
		777189 PTN12_MOUSE (1-800): 0: 815: 35.03		PPIP2_MOUSE (2-324): 5.52e-54: 184: 41.98
+	Hs
		220799 PTN18_HUMAN (3-349): 2.26e-131: 401: 40.12		PPIP1_HUMAN (1-415): 1.06e-80: 256: 87.98
+	Mm
		1021932 PTN18_MOUSE (3-333): 8.1e-130: 396: 41.74		PPIP1_MOUSE (1-415): 1.23e-81: 258: 100.00
+	Hs
		1408280 PTN18_HUMAN (3-349): 2.26e-131: 401: 40.12		PPIP2_HUMAN (2-324): 5.35e-54: 184: 42.90
+	Mm
		1222361 PTN18_MOUSE (3-333): 8.1e-130: 396: 41.74		PPIP2_MOUSE (2-324): 5.52e-54: 184: 41.98
+	Mm
		767034 PTN11_MOUSE (2-320): 2.87e-125: 389: 31.66		ITSN1_MOUSE (339-414): 8.5e-10: 63.2: 19.74
+	Hs
		220739 PTN1_HUMAN (34-288): 1.41e-42: 162: 36.40		PPIP1_HUMAN (1-415): 1.06e-80: 256: 87.98
+	Hs
		659019 PTPRG_HUMAN (20-295): 4.27e-53: 202: 24.13		FCHO2_HUMAN (2-357): 1.72e-49: 181: 18.94