HitPredict

Interactor 1: PLK1 (P34331)
Serine/threonine-protein kinase plk-1 (EC 2.7.11.21) (Polo-like kinase 1)
Gene: plk-1

Interactor 2: MEX5 (Q9XUB2)
Zinc finger protein mex-5
Gene: mex-5

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	18199581, 35442950
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 649 Ce			1 468
+	Ce
		711432 PLK1_CAEEL (1-649): 0: 633: 100.00		MEX6_CAEEL (1-468): 0: 599: 69.31
+	Ce
		1341487 PLK2_CAEEL (5-635): 0: 569: 66.30		MEX5_CAEEL (1-468): 0: 624: 100.00
+	Ce
		998567 PLK2_CAEEL (5-635): 0: 569: 66.30		MEX6_CAEEL (1-468): 0: 599: 69.31
+	Ce
		105055 PLK1_CAEEL (1-649): 0: 633: 100.00		G5ECB9_CAEEL (131-375): 1.79e-65: 220: 21.60
+	Ce
		185342 PLK1_CAEEL (1-649): 0: 633: 100.00		O18251_CAEEL (204-370): 1.21e-46: 161: 22.94
+	Ce
		107250 PLK1_CAEEL (1-649): 0: 633: 100.00		POS1_CAEEL (202-341): 9.48e-40: 145: 26.06
+	Ce
		105017 PLK1_CAEEL (1-649): 0: 633: 100.00		MOE1_CAEEL (179-361): 2.25e-31: 126: 26.46
+	Ce
		711595 PLK1_CAEEL (1-649): 0: 633: 100.00		MOE2_CAEEL (259-361): 2.28e-28: 117: 38.84