HitPredict

Interactor 1: LIN36 (P34427)
Protein lin-36 (Abnormal cell lineage protein 36)
Gene: lin-36

Interactor 2: IFA1 (P90901)
Intermediate filament protein ifa-1 (Cel IF A1) (Intermediate filament protein A1) (IF-A1)
Gene: ifa-1

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	12679813, 10615043, 14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 962 Ce			1 575
+	Ce
		711942 LIN36_CAEEL (1-962): 0: 852: 100.00		IFB2_CAEEL (55-571): 7.8e-69: 233: 38.61
+	Ce
		711935 LIN36_CAEEL (1-962): 0: 852: 100.00		IFA4_CAEEL (3-575): 6.43e-61: 213: 60.21
+	Ce
		137628 LIN36_CAEEL (1-962): 0: 852: 100.00		IFA2_CAEEL (2-574): 4.44e-60: 211: 62.48
+	Dr
		71432 NIPLB_DANRE (392-925): 3.04e-10: 66.6: 11.71		B3DKC5_DANRE (46-573): 2.28e-68: 235: 28.52
+	Hs
		359942 MDC1_HUMAN (374-961): 1.09e-12: 74.8: 8.29		LMNA_HUMAN (39-575): 6.21e-55: 198: 26.96
+	Hs
		360224 TITIN_HUMAN (379-957): 2.15e-11: 70.6: 9.40		LMNA_HUMAN (39-575): 6.21e-55: 198: 26.96
+	Hs
		360045 NIPBL_HUMAN (446-879): 5.57e-09: 62.6: 15.18		LMNA_HUMAN (39-575): 6.21e-55: 198: 26.96
+	Hs
		595271 NIPBL_HUMAN (446-879): 5.57e-09: 62.6: 15.18		LMNB1_HUMAN (39-575): 3.86e-51: 186: 27.64
+	Hs
		517802 NFH_HUMAN (483-957): 3.8e-20: 98.7: 11.07		AINX_HUMAN (66-421): 2.06e-31: 129: 31.76
+	Hs
		443464 ANK2_HUMAN (380-950): 3.86e-12: 73.2: 10.48		VIME_HUMAN (60-424): 3.62e-35: 139: 29.59
+	Hs
		965108 ANK2_HUMAN (380-950): 3.86e-12: 73.2: 10.48		AINX_HUMAN (66-421): 2.06e-31: 129: 31.76