HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: TNK1 (Q13470)
Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1)
Gene: TNK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 666
+	Hs
		337370 HSP74_HUMAN (1-840): 0: 993: 100.00		ABL1_HUMAN (22-643): 2.23e-124: 397: 21.38
+	Hs
		383646 HSP74_HUMAN (1-840): 0: 993: 100.00		ERBB2_HUMAN (65-631): 7.95e-122: 393: 22.82
+	Hs
		412053 HSP74_HUMAN (1-840): 0: 993: 100.00		FYN_HUMAN (3-393): 4.79e-122: 375: 23.79
+	Hs
		522818 HSP74_HUMAN (1-840): 0: 993: 100.00		SRC_HUMAN (2-393): 5.17e-122: 375: 25.51
+	Hs
		320789 HS74L_HUMAN (1-840): 0: 959: 63.21		ERBB2_HUMAN (65-631): 7.95e-122: 393: 22.82
+	Hs
		412286 HS105_HUMAN (1-840): 0: 938: 62.95		FYN_HUMAN (3-393): 4.79e-122: 375: 23.79
+	Hs
		523090 HS105_HUMAN (1-840): 0: 938: 62.95		SRC_HUMAN (2-393): 5.17e-122: 375: 25.51
+	Hs
		1072565 HS105_HUMAN (1-840): 0: 938: 62.95		EPHA7_HUMAN (83-422): 4.05e-116: 373: 31.67
+	Hs
		338020 HSP74_HUMAN (1-840): 0: 993: 100.00		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59
+	Hs
		320783 HS74L_HUMAN (1-840): 0: 959: 63.21		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59
+	Hs
		338778 HS105_HUMAN (1-840): 0: 938: 62.95		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59
+	Hs
		337324 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ABL1_HUMAN (22-643): 2.23e-124: 397: 21.38
+	Hs
		411965 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		FYN_HUMAN (3-393): 4.79e-122: 375: 23.79
+	Hs
		503340 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		SRC_HUMAN (2-393): 5.17e-122: 375: 25.51
+	Hs
		433227 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		YES_HUMAN (89-393): 3.05e-119: 368: 28.20
+	Hs
		411570 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		LCK_HUMAN (91-392): 1.46e-113: 352: 30.46
+	Hs
		442767 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		HCK_HUMAN (98-389): 7.47e-109: 340: 29.80
+	Hs
		338520 Q59EJ3_HUMAN (571-686): 5.38e-20: 97.4: 23.93		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59
+	Hs
		337839 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59
+	Hs
		338516 Q53GZ6_HUMAN (564-692): 6.29e-20: 97: 16.92		EGFR_HUMAN (89-373): 4.38e-46: 178: 36.59