HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: HPBP1 (Q9NZL4)
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Gene: HSPBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	14503850, 19659607
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000774 - adenyl-nucleotide exchange factor activity GO:0006457 - protein folding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 359
+	Hs
		714147 HSP74_HUMAN (1-840): 0: 993: 100.00		IMA5_HUMAN (51-301): 1.38e-24: 106: 15.02
+	Sc
		694577 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		FES1_YEAST (45-330): 8.76e-62: 201: 19.66
+	Hs
		504872 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		483807 HS71B_HUMAN (571-686): 1.59e-19: 95.5: 23.93		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		714085 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		564199 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00
+	Hs
		134830 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39