HitPredict

Interactor 1: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Interactor 2: Q8WTJ8 (Q8WTJ8)
RING-type domain-containing protein
Gene: grif-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	18692475, unassigned701
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Ce			1 305
+	Hs
		1318738 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM2_HUMAN (7-287): 6.37e-45: 163: 17.42
+	Hs
		1285831 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI43_HUMAN (6-292): 1.72e-45: 161: 14.87
+	Hs
		1336390 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI39_HUMAN (10-290): 7.62e-45: 161: 15.86
+	Hs
		1318719 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM5_HUMAN (6-295): 1.85e-43: 157: 12.71
+	Hs
		262201 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM3_HUMAN (14-273): 4.68e-42: 156: 15.85
+	Hs
		849314 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI26_HUMAN (6-292): 8.89e-44: 158: 12.16
+	Hs
		537142 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI27_HUMAN (6-292): 7.86e-43: 155: 14.53
+	Hs
		584907 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		RO52_HUMAN (6-292): 5.88e-44: 157: 15.54
+	Hs
		262161 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRIM3_HUMAN (14-273): 4.68e-42: 156: 15.85
+	Hs
		536760 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI27_HUMAN (6-292): 7.86e-43: 155: 14.53
+	Hs
		1356055 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM1_HUMAN (7-298): 7.15e-40: 149: 16.71
+	Hs
		1377469 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI17_HUMAN (11-291): 1.08e-40: 149: 13.79
+	Hs
		1151762 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		Q6GX22_HUMAN (10-298): 3.14e-39: 147: 16.57
+	Hs
		1354526 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI10_HUMAN (6-293): 1.3e-39: 146: 13.42
+	Hs
		175730 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI18_HUMAN (10-294): 1.08e-38: 146: 14.37
+	Hs
		849316 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI32_HUMAN (6-280): 1.55e-39: 148: 18.48
+	Hs
		175653 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI18_HUMAN (10-294): 1.08e-38: 146: 14.37
+	Hs
		734819 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI23_HUMAN (12-226): 1.23e-18: 88.1: 17.57
+	Hs
		734563 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI23_HUMAN (12-226): 1.23e-18: 88.1: 17.57
+	Hs
		849352 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		SH3R1_HUMAN (9-174): 1.05e-15: 79.3: 16.57