HitPredict

Interactor 1: BIP (P29844)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78 homolog) (Binding-immunoglobulin protein homolog) (BiP) (Heat shock 70 kDa protein cognate 3) (Heat shock protein cognate 72)
Gene: Hsc70-3

Interactor 2: Q9V3E9 (Q9V3E9)
RNA polymerase II-associated protein 3
Gene: spag

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24394412
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP70~TPR_11
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 656 Dm			1 534
+	Hs
		535673 BIP_HUMAN (20-656): 0: 940: 82.13		CHIP_HUMAN (72-349): 1.21e-44: 161: 15.83
+	At
		85549 HS704_ARATH (24-652): 0: 936: 63.62		OEP61_ARATH (9-452): 7.24e-44: 165: 17.89
+	Hs
		226689 HSP7C_HUMAN (27-637): 0: 933: 64.17		SGTA_HUMAN (37-299): 2.26e-46: 166: 22.47
+	Hs
		761538 HS71L_HUMAN (25-647): 0: 935: 61.50		CHIP_HUMAN (72-349): 1.21e-44: 161: 15.83
+	Mm
		989295 HSP7C_MOUSE (27-637): 0: 933: 64.17		CHIP_MOUSE (72-349): 8.51e-45: 162: 15.83
+	Hs
		536809 HSP7C_HUMAN (27-637): 0: 933: 64.17		PPP5_HUMAN (72-250): 5.53e-43: 161: 28.49
+	Mm
		989266 HSP7C_MOUSE (27-637): 0: 933: 64.17		SGTA_MOUSE (37-319): 2.42e-42: 155: 20.21
+	Hs
		185382 BIP_HUMAN (20-656): 0: 940: 82.13		OGT1_HUMAN (7-447): 3.36e-36: 145: 10.99
+	Mm
		989249 HSP7C_MOUSE (27-637): 0: 933: 64.17		PPP5_MOUSE (68-305): 1.35e-39: 152: 23.53
+	Hs
		185383 HSP7C_HUMAN (27-637): 0: 933: 64.17		OGT1_HUMAN (7-447): 3.36e-36: 145: 10.99
+	Hs
		761411 HS71L_HUMAN (25-647): 0: 935: 61.50		TOM34_HUMAN (88-372): 2.5e-30: 122: 18.03
+	Hs
		535223 BIP_HUMAN (20-656): 0: 940: 82.13		TMTC3_HUMAN (106-484): 3.82e-18: 90.1: 10.30
+	At
		1441393 HS704_ARATH (24-652): 0: 936: 63.62		HSOP1_ARATH (102-376): 1.29e-18: 91.3: 15.36
+	Hs
		535448 BIP_HUMAN (20-656): 0: 940: 82.13		DNJC7_HUMAN (2-252): 1.51e-14: 78.2: 14.82
+	Hs
		1198774 Q53FA3_HUMAN (25-647): 0: 935: 61.34		DNJC7_HUMAN (2-252): 1.51e-14: 78.2: 14.82
+	Hs
		761494 HS71L_HUMAN (25-647): 0: 935: 61.50		DNJC7_HUMAN (2-252): 1.51e-14: 78.2: 14.82
+	Hs
		534699 BIP_HUMAN (20-656): 0: 940: 82.13		STIP1_HUMAN (53-317): 8.3e-10: 63.1: 9.73
+	Hs
		317978 HSP7C_HUMAN (27-637): 0: 933: 64.17		TOM70_HUMAN (65-194): 1.27e-11: 69.3: 31.66
+	Hs
		731003 HS71L_HUMAN (25-647): 0: 935: 61.50		STIP1_HUMAN (53-317): 8.3e-10: 63.1: 9.73
+	Hs
		536600 HSP7C_HUMAN (27-637): 0: 933: 64.17		STIP1_HUMAN (53-317): 8.3e-10: 63.1: 9.73