HitPredict

Interactor 1: AP1S1 (P35181)
AP-1 complex subunit sigma-1 (Clathrin assembly protein complex 1 sigma-1 small chain) (Clathrin coat assembly protein AP19) (Clathrin coat-associated protein AP19) (Golgi adaptor AP-1 19 kDa adaptin) (HA1 19 kDa subunit) (Sigma1-adaptin)
Gene: APS1

Interactor 2: AP1G1 (Q12028)
AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin)
Gene: APL4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 11283351, 16429126, 34688652, 37968396, 22940862, 16554755, 18467557, 22615397, 23056294
Identification Methods two hybrid pooling approach, affinity chromatography technology, two hybrid, pull down, protein complementation assay, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0030121 - AP-1 adaptor complex
GO:0035615 - clathrin adaptor activity
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024