HitPredict

Interactor 1: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 332 Hs			1 191
+	Hs
		319046 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RHOC_HUMAN (6-185): 8.96e-86: 252: 42.25
+	Hs
		319059 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93
+	Hs
		953777 CRBG1_HUMAN (26-329): 1.15e-30: 124: 23.53		RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81
+	Hs
		466119 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RHOC_HUMAN (6-185): 8.96e-86: 252: 42.25
+	Hs
		715522 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RHOB_HUMAN (6-191): 9.7e-86: 252: 40.93
+	Hs
		176260 SYNJ2_HUMAN (52-321): 7.17e-21: 95.7: 12.64		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		319060 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RAC1_HUMAN (2-191): 2.94e-77: 230: 39.09
+	Hs
		319049 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RAC2_HUMAN (2-191): 3.12e-74: 223: 38.07
+	Hs
		176256 SYNJ2_HUMAN (52-321): 7.17e-21: 95.7: 12.64		RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81
+	Hs
		319056 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81
+	Hs
		319064 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RHOG_HUMAN (2-191): 6.18e-73: 220: 37.06
+	Hs
		319057 K0754_HUMAN (40-331): 3.65e-20: 93.8: 18.24		RHOA_HUMAN (6-191): 3.36e-72: 218: 38.86
+	Ce
		145082 UNC89_CAEEL (7-294): 1.71e-16: 82.6: 12.19		RAC1_CAEEL (2-191): 2.77e-76: 228: 40.10
+	Hs
		580886 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RAC2_HUMAN (2-191): 3.12e-74: 223: 38.07
+	Ce
		110130 UNC89_CAEEL (7-294): 1.71e-16: 82.6: 12.19		G5EBV3_CAEEL (3-191): 6.82e-73: 220: 40.82
+	Hs
		715508 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RAC3_HUMAN (2-171): 1.04e-73: 221: 41.81
+	Hs
		715509 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		CDC42_HUMAN (2-191): 2.37e-72: 218: 40.61
+	Hs
		715512 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RHOA_HUMAN (6-191): 3.36e-72: 218: 38.86
+	Hs
		601181 MARCS_HUMAN (1-322): 1.8e-16: 81: 100.00		RHOQ_HUMAN (5-190): 9.56e-72: 217: 39.49
+	Ce
		145083 UNC89_CAEEL (7-294): 1.71e-16: 82.6: 12.19		CDC42_CAEEL (2-181): 6.45e-49: 159: 40.64