HitPredict

Interactor 1: PTN11 (P35235)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)
Gene: Ptpn11

Interactor 2: SHPS1 (P97797)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
Gene: Sirpa

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.738

The method score is based on:

Property Details
Experiments 15699129, 8810330, 9507023, 18450421, 11970986, 18233962, 18471880
Identification Methods affinity chromatography technology, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:1990782 - protein tyrosine kinase binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 593
Mm

1 513
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024