HitPredict

Interactor 1: SC6A1 (P30531)
Sodium- and chloride-dependent GABA transporter 1 (GAT-1) (Solute carrier family 6 member 1)
Gene: SLC6A1

Interactor 2: STX1A (Q16623)
Syntaxin-1A (Neuron-specific antigen HPC-1)
Gene: STX1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	9698305, 11960023, 11017172
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 599 Hs			1 288
+	Mm
		727592 SC6A1_MOUSE (1-599): 0: 776: 98.00		STX1B_MOUSE (1-288): 5.22e-85: 258: 83.33
+	Hs
		1159662 SC6A5_HUMAN (1-577): 0: 693: 43.88		STX1A_HUMAN (1-288): 1.67e-84: 256: 100.00
+	Hs
		727563 SC6A4_HUMAN (3-580): 0: 663: 42.20		STX1A_HUMAN (1-288): 1.67e-84: 256: 100.00
+	Mm
		204927 SC6A3_MOUSE (2-583): 0: 651: 43.15		STX1A_MOUSE (1-288): 3.71e-86: 261: 98.26
+	Hs
		1033927 SC6A3_HUMAN (2-583): 0: 654: 43.41		STX1A_HUMAN (1-288): 1.67e-84: 256: 100.00
+	Hs
		870445 SC6A9_HUMAN (10-577): 0: 647: 42.37		STX1A_HUMAN (1-288): 1.67e-84: 256: 100.00
+	Hs
		663631 SC6A2_HUMAN (34-576): 0: 645: 46.21		STX1A_HUMAN (1-288): 1.67e-84: 256: 100.00
+	Ce
		194915 NTDO_CAEEL (3-596): 0: 595: 37.22		STX1A_CAEEL (2-283): 8.08e-75: 232: 64.31
+	Hs
		869588 SC6A8_HUMAN (2-573): 0: 623: 50.51		STX4_HUMAN (1-287): 1.23e-63: 203: 43.58
+	Hs
		727529 SC6A6_HUMAN (21-575): 0: 622: 51.15		STX4_HUMAN (1-287): 1.23e-63: 203: 43.58
+	Hs
		189451 SC6A8_HUMAN (2-573): 0: 623: 50.51		STX7_HUMAN (37-286): 7.02e-50: 167: 25.30
+	Hs
		189432 SC6A6_HUMAN (21-575): 0: 622: 51.15		STX7_HUMAN (37-286): 7.02e-50: 167: 25.30
+	Hs
		1087279 S6A15_HUMAN (19-555): 1.02e-147: 445: 25.37		STX4_HUMAN (1-287): 1.23e-63: 203: 43.58
+	Hs
		1294830 S6A15_HUMAN (19-555): 1.02e-147: 445: 25.37		STX12_HUMAN (26-271): 2.33e-51: 171: 24.50
+	Hs
		189834 S6A15_HUMAN (19-555): 1.02e-147: 445: 25.37		STX7_HUMAN (37-286): 7.02e-50: 167: 25.30