Interactor 1: RPB2 (P30876)
DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) (RNA-directed RNA polymerase II subunit RPB2) (EC 2.7.7.48)
Gene: POLR2B
Interactor 2: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.922 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9201987, 33961781, 24981860, 35271311, unassigned3799 |
| Identification Methods | pull down, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | RNA_pol_N~RNA_pol_Rpb2_1, RNA_pol_N~RNA_pol_Rpb2_6 |
| Common GO terms | GO:0003677 - DNA binding GO:0003899 - DNA-directed RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex and 2 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
