Interactor 1: SCN4A (P35499)
Sodium channel protein type 4 subunit alpha (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)
Gene: SCN4A

Interactor 2: SCN1B (Q07699)
Sodium channel subunit beta-1
Gene: SCN1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.666

The method score is based on:

Property Details
Experiments 30190309
Identification Methods 3D electron microscopy, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~V-set
Common GO terms GO:0001518 - voltage-gated sodium channel complex
GO:0005248 - voltage-gated sodium channel activity
GO:0005886 - plasma membrane
GO:0035725 - sodium ion transmembrane transport
GO:0086002 - cardiac muscle cell action potential involved in contraction
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1836
Hs

1 218
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024