Interactor 1: NTRK1 (P35739)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Slow nerve growth factor receptor) (p140-TrkA) (Trk-A)
Gene: NTRK1

Interactor 2: KDIS (Q9EQG6)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: Kidins220

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16284401
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~I-set, Ank_2~I-set
Common GO terms GO:0005770 - late endosome
GO:0010976 - positive regulation of neuron projection development
GO:0032991 - protein-containing complex
GO:0038180 - nerve growth factor signaling pathway
GO:1990090 - cellular response to nerve growth factor stimulus
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 799
Rn

1 1762
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024