HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	33961781, 28514442, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 513
+	Hs
		971765 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ABI1_HUMAN (1-513): 1.58e-95: 300: 60.43
+	Hs
		972060 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ABI2_HUMAN (1-513): 2.17e-91: 290: 100.00
+	Hs
		729831 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		SRC8_HUMAN (271-507): 3.77e-33: 134: 17.84
+	Hs
		319058 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		K0754_HUMAN (111-451): 3.57e-28: 121: 16.38
+	Hs
		319052 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		K0754_HUMAN (111-451): 3.57e-28: 121: 16.38
+	Hs
		319061 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (111-451): 3.57e-28: 121: 16.38
+	Mm
		990024 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		ARHG6_MOUSE (419-508): 2.4e-27: 118: 37.78
+	Hs
		971514 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ARHG7_HUMAN (451-508): 2.17e-18: 90.8: 41.38
+	Hs
		729825 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		ARHG7_HUMAN (451-508): 2.17e-18: 90.8: 41.38
+	Mm
		972237 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		DBNL_MOUSE (293-508): 1.65e-17: 87: 22.07
+	Mm
		972217 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		SRBS2_MOUSE (371-509): 7.75e-17: 85.9: 21.53
+	Hs
		320229 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		320272 V9HW98_HUMAN (3-243): 4.41e-144: 405: 65.43		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		320213 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		971389 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Hs
		729733 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		GRB2_HUMAN (454-510): 1.09e-17: 83.7: 37.93
+	Mm
		990056 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		ARHG7_MOUSE (451-508): 1.09e-17: 88.5: 43.10
+	Hs
		320230 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		971817 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SH3R3_HUMAN (370-508): 3.58e-10: 64.7: 20.14
+	Hs
		730084 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		SH3R3_HUMAN (370-508): 3.58e-10: 64.7: 20.14