HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 26578655, 28205554, 32296183, unassigned1304, 36931259, 15778465
Identification Methods fluorescent resonance energy transfer, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, cross-linking study, tandem affinity purification
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001836 - release of cytochrome c from mitochondria
GO:0003334 - keratinocyte development
GO:0005615 - extracellular space
GO:0005634 - nucleus
and 31 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 248
Hs

1 248
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Service provided by Combinatics, Japan

Last updated: 11Aug2025