HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 33961781, 36931259, 35575683, 28524877, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0008104 - intracellular protein localization
GO:0070062 - extracellular exosome
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 248
Hs

1 246
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Mm
+ Zm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025