HitPredict

Interactor 1: MID2 (P36027)
Cell wall integrity sensor MID2 (Mating pheromone-induced death protein 2) (Protein kinase A interference protein 1) (Serine-rich multicopy suppressor protein 1)
Gene: MID2

Interactor 2: RHO5 (P53879)
GTP-binding protein RHO5
Gene: RHO5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	30670610
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 376 Sc			1 331
+	Hs
		900423 ANK3_HUMAN (6-226): 1.02e-25: 111: 21.49		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		925238 ANK3_HUMAN (6-226): 1.02e-25: 111: 21.49		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		950953 ANK3_HUMAN (6-226): 1.02e-25: 111: 21.49		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Ce
		136800 UNC89_CAEEL (5-232): 4.76e-09: 60.5: 12.07		RHO1_CAEEL (5-220): 1.03e-90: 270: 40.28
+	Hs
		893947 ANK3_HUMAN (6-226): 1.02e-25: 111: 21.49		CDC42_HUMAN (1-229): 1.18e-70: 219: 44.11
+	Hs
		297820 K0754_HUMAN (5-231): 3.22e-17: 86: 15.00		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Hs
		297823 K0754_HUMAN (5-231): 3.22e-17: 86: 15.00		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		297819 K0754_HUMAN (5-231): 3.22e-17: 86: 15.00		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		297827 K0754_HUMAN (5-231): 3.22e-17: 86: 15.00		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Hs
		297812 K0754_HUMAN (5-231): 3.22e-17: 86: 15.00		RAC2_HUMAN (1-231): 4.56e-72: 223: 43.72
+	Hs
		195972 PLXB1_HUMAN (18-241): 4.84e-11: 66.7: 15.15		RHOA_HUMAN (5-229): 1.44e-77: 237: 40.89
+	Ce
		104464 UNC89_CAEEL (5-232): 4.76e-09: 60.5: 12.07		G5EBV3_CAEEL (2-230): 6.74e-78: 238: 43.23
+	Ce
		136794 UNC89_CAEEL (5-232): 4.76e-09: 60.5: 12.07		CDC42_CAEEL (1-230): 1.49e-77: 237: 45.22
+	Hs
		925603 TARA_HUMAN (15-225): 2.39e-10: 64.4: 16.95		RAC1_HUMAN (1-230): 8.61e-76: 232: 43.91
+	Hs
		892586 TARA_HUMAN (15-225): 2.39e-10: 64.4: 16.95		RAC3_HUMAN (1-218): 5.72e-73: 225: 44.95
+	Hs
		951324 TARA_HUMAN (15-225): 2.39e-10: 64.4: 16.95		RHOG_HUMAN (1-229): 1.07e-72: 225: 41.92
+	Ce
		136793 UNC89_CAEEL (5-232): 4.76e-09: 60.5: 12.07		RAC1_CAEEL (1-229): 3.95e-74: 228: 42.36
+	Hs
		564677 TARA_HUMAN (15-225): 2.39e-10: 64.4: 16.95		RHOQ_HUMAN (4-222): 7.24e-56: 182: 42.92