HitPredict

Interactor 1: NAC1 (P32418)
Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1)
Gene: SLC8A1

Interactor 2: S1A7A (Q86SG5)
Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)
Gene: S100A7A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31837246
Identification Methods	fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 973 Hs			1 101
+	Hs
		731756 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AB_HUMAN (2-95): 3.81e-33: 112: 35.05
+	Hs
		657023 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A1_HUMAN (2-94): 5.58e-33: 111: 20.83
+	Hs
		736464 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AA_HUMAN (2-90): 9.33e-33: 111: 24.72
+	Hs
		724537 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A7_HUMAN (1-101): 3.12e-31: 107: 94.06
+	Hs
		682455 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100P_HUMAN (4-93): 5.01e-31: 106: 29.03
+	Hs
		736471 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100Z_HUMAN (2-98): 3.73e-30: 104: 23.00
+	Hs
		444914 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A9_HUMAN (4-100): 1.25e-29: 103: 25.00
+	Hs
		686782 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A4_HUMAN (2-96): 3.98e-29: 102: 24.49
+	Hs
		706072 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A2_HUMAN (1-97): 1.93e-28: 100: 22.00
+	Hs
		736462 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A3_HUMAN (2-98): 7.97e-28: 98.8: 18.45
+	Hs
		407590 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100B_HUMAN (4-93): 2.66e-26: 94.6: 24.73
+	Hs
		736466 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AC_HUMAN (4-93): 6.6e-26: 93.8: 24.73
+	Hs
		424146 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A8_HUMAN (2-96): 2.03e-25: 92.7: 23.47
+	Hs
		445135 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A6_HUMAN (2-92): 1.32e-24: 90.4: 24.47
+	Hs
		736461 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10A5_HUMAN (2-94): 1.72e-24: 90: 22.92
+	Hs
		736472 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AD_HUMAN (4-84): 8.69e-21: 80.7: 20.24
+	Hs
		736473 NAC1_HUMAN (1-973): 0: 1124: 100.00		S10AE_HUMAN (4-84): 1.11e-19: 78.4: 21.69
+	Hs
		711962 NAC1_HUMAN (1-973): 0: 1124: 100.00		S100G_HUMAN (5-84): 2.81e-15: 66.5: 25.30