HitPredict

Interactor 1: CGM2 (P36613)
Cyclin mcs2 (Mitotic catastrophe suppressor 2)
Gene: mcs2

Interactor 2: CRK1 (Q12126)
Serine/threonine-protein kinase crk1 (EC 2.7.11.23) (Mitotic catastrophe suppressor 6)
Gene: CRK1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.935

The method score is based on:

Property Details
Experiments 8557036, 8557037, 9857180, 10226032, 15555586
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C_2~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0007049 - cell cycle
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0051301 - cell division
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 322
Sp

1 335
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Hs
+ Mm
+ At
+ Hs
+ Dm
+ At
+ Dm
+ At
+ At
+ At
+ At
+ Dm
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024