Interactor 1: HIR1 (P32479)
Protein HIR1 (Histone transcription regulator 1)
Gene: HIR1
Interactor 2: HIR2 (P32480)
Protein HIR2 (Histone transcription regulator 2)
Gene: HIR2
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.963 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9504914, 9001207, 16264190, 38925115, 21782987, 37968396, 21179020 |
| Identification Methods | coimmunoprecipitation, affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hira~Hira |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000417 - HIR complex GO:0000785 - chromatin GO:0003714 - transcription corepressor activity GO:0005634 - nucleus and 5 others more... |
| Homologous interactions | 16 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
