HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30344098, 17511879
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1863
+	Hs
		749316 PP1A_HUMAN (1-323): 0: 579: 90.66		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749317 PP1B_HUMAN (1-322): 0: 560: 86.89		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749356 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		737950 PP1G_HUMAN (1-323): 0: 603: 100.00		TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12
+	Hs
		536746 PP1G_HUMAN (1-323): 0: 603: 100.00		TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74
+	Hs
		738001 PP1G_HUMAN (1-323): 0: 603: 100.00		BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98
+	Hs
		738025 PP1G_HUMAN (1-323): 0: 603: 100.00		TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30