HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 28514442, 30344098, 33961781, 34349018, 36652389, 24366813
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos, Metallophos~STPPase_N, STPPase_N~STPPase_N
Common GO terms GO:0000165 - MAPK cascade
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
and 14 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 323
Hs

1 327
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024