HitPredict

Interactor 1: EGR1 (P18146)
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)
Gene: EGR1

Interactor 2: M3K8 (P41279)
Mitogen-activated protein kinase kinase kinase 8 (EC 2.7.11.25) (Cancer Osaka thyroid oncogene) (Proto-oncogene c-Cot) (Serine/threonine-protein kinase cot) (Tumor progression locus 2) (TPL-2)
Gene: MAP3K8

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	19374776
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~zf-C2H2
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 467
+	Hs
		575289 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		AKT1_HUMAN (49-466): 1.05e-133: 396: 16.17
+	Hs
		575541 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		KCC1G_HUMAN (119-462): 1.11e-105: 324: 21.97
+	Hs
		575594 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		PAK6_HUMAN (144-388): 1.71e-27: 117: 32.67
+	Hs
		1023079 ZN695_HUMAN (333-536): 6.92e-37: 145: 15.00		STK4_HUMAN (116-419): 2.68e-103: 318: 25.89
+	Hs
		1129231 ZN569_HUMAN (13-310): 2.93e-72: 245: 8.82		STK24_HUMAN (144-386): 6.54e-35: 137: 34.40