HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PP1R7 (Q15435)
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene: PPP1R7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.979

Property	Details
Experiments	26186194, 28514442, 30344098, 23414517, 33961781, 27880917, 27173435, 28330616, 34824462, 24366813
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LRR_9~Metallophos, LRR_9~STPPase_N
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 360
+	Hs
		905917 PP1A_HUMAN (1-323): 0: 579: 90.66		PP1R7_HUMAN (1-360): 8.35e-58: 193: 100.00
+	Mm
		906251 PP1A_MOUSE (1-323): 0: 579: 90.36		PP1R7_MOUSE (1-360): 1.22e-55: 187: 93.35
+	Hs
		906470 PP1B_HUMAN (1-322): 0: 560: 86.89		PP1R7_HUMAN (1-360): 8.35e-58: 193: 100.00
+	Hs
		737799 PP1G_HUMAN (1-323): 0: 603: 100.00		SCRIB_HUMAN (110-360): 8.96e-32: 128: 19.38
+	Sp
		605293 PP12_SCHPO (8-322): 0: 539: 76.51		SDS22_SCHPO (93-358): 1.22e-54: 184: 50.00
+	Hs
		905890 PP1A_HUMAN (1-323): 0: 579: 90.66		SCRIB_HUMAN (110-360): 8.96e-32: 128: 19.38
+	Dm
		819228 PP11_DROME (5-323): 0: 569: 88.92		Q9VEK8_DROME (124-360): 2e-32: 125: 36.71
+	Hs
		737994 PP1G_HUMAN (1-323): 0: 603: 100.00		ERBIN_HUMAN (24-160): 1.95e-18: 89.1: 14.11
+	Ca
		1124021 Q59N42_CANAL (5-323): 0: 555: 82.50		Q5AHH6_CANAL (53-266): 1.98e-35: 134: 30.73
+	Hs
		906454 PP1B_HUMAN (1-322): 0: 560: 86.89		SCRIB_HUMAN (110-360): 8.96e-32: 128: 19.38
+	Dm
		819306 PP1B_DROME (1-323): 0: 552: 82.48		Q9VEK8_DROME (124-360): 2e-32: 125: 36.71
+	Dm
		524647 PP12_DROME (5-303): 0: 551: 93.31		Q9VEK8_DROME (124-360): 2e-32: 125: 36.71
+	Hs
		737779 PP1G_HUMAN (1-323): 0: 603: 100.00		FLII_HUMAN (230-360): 4.87e-13: 72.5: 16.67
+	Sc
		696298 PP12_YEAST (3-304): 0: 550: 85.76		SDS22_YEAST (19-287): 1.88e-31: 123: 29.60
+	Dm
		984195 PP13_DROME (5-303): 0: 547: 91.64		Q9VEK8_DROME (124-360): 2e-32: 125: 36.71
+	Hs
		906094 PP1A_HUMAN (1-323): 0: 579: 90.66		ERBIN_HUMAN (24-160): 1.95e-18: 89.1: 14.11
+	Dm
		524622 PP12_DROME (5-303): 0: 551: 93.31		SCRIB_DROME (132-360): 5.73e-27: 114: 18.82
+	Hs
		905863 PP1A_HUMAN (1-323): 0: 579: 90.66		FLII_HUMAN (230-360): 4.87e-13: 72.5: 16.67
+	Hs
		906437 PP1B_HUMAN (1-322): 0: 560: 86.89		FLII_HUMAN (230-360): 4.87e-13: 72.5: 16.67
+	Ce
		800282 GLC7A_CAEEL (1-323): 0: 549: 83.28		SDS22_CAEEL (18-176): 2.37e-10: 62.9: 22.22