HitPredict

Interactor 1: BRR2 (P32639)
Pre-mRNA-splicing helicase BRR2 (EC 3.6.4.13) (Protein Snu246)
Gene: BRR2

Interactor 2: RU17 (Q00916)
U1 small nuclear ribonucleoprotein 70 kDa homolog (U1 70K) (U1 snRNP 70 kDa homolog) (U1-70K) (U1 small nuclear ribonucleoprotein SNP1) (U1 snRNP protein SNP1)
Gene: SNP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	11290703, 9207794
Identification Methods	two hybrid, coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2163 Sc			1 300
+	Hs
		289409 U520_HUMAN (16-2163): 0: 1598: 38.93		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00
+	Sc
		403421 BRR2_YEAST (1-2163): 0: 1534: 100.00		PABP_YEAST (75-258): 1.85e-20: 93.4: 16.30
+	Hs
		550360 ASCC3_HUMAN (58-2162): 0: 1386: 30.92		PABP1_HUMAN (99-262): 4.51e-27: 112: 17.68
+	Sp
		724856 BRR2_SCHPO (5-2162): 0: 1396: 40.91		PABP_SCHPO (34-258): 9.4e-21: 94.1: 13.78
+	Sp
		151411 YE02_SCHPO (377-925): 4.57e-87: 311: 21.59		RU17_SCHPO (7-267): 1.88e-50: 169: 34.48
+	Hs
		472944 DDX17_HUMAN (1345-1753): 1.48e-96: 331: 11.35		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00
+	Hs
		472441 DDX5_HUMAN (1344-1752): 1.09e-92: 316: 11.35		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00
+	Hs
		1120263 DDX17_HUMAN (1345-1753): 1.48e-96: 331: 11.35		HNRPD_HUMAN (72-194): 9.99e-30: 117: 24.00
+	Mm
		915297 DDX17_MOUSE (1345-1753): 2e-97: 331: 11.35		TIA1_MOUSE (102-299): 1.26e-27: 112: 11.57
+	Hs
		473035 DDX23_HUMAN (1275-1768): 5.4e-82: 291: 13.30		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00
+	Hs
		608572 DDX5_HUMAN (1344-1752): 1.09e-92: 316: 11.35		ROA0_HUMAN (102-296): 3.65e-28: 112: 17.35
+	Mm
		915325 Q8BTS0_MOUSE (1344-1752): 1.43e-92: 316: 11.35		TIA1_MOUSE (102-299): 1.26e-27: 112: 11.57
+	Hs
		472503 MTREX_HUMAN (355-1000): 3.38e-76: 278: 17.83		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00
+	Sc
		403562 MTR4_YEAST (364-927): 1.41e-92: 329: 20.07		PABP_YEAST (75-258): 1.85e-20: 93.4: 16.30
+	Mm
		1000097 DDX5_MOUSE (1344-1752): 5.49e-93: 317: 11.35		TIAR_MOUSE (101-297): 4.53e-23: 99.5: 13.15
+	Sp
		151533 YE02_SCHPO (377-925): 4.57e-87: 311: 21.59		PABP_SCHPO (34-258): 9.4e-21: 94.1: 13.78
+	Hs
		472739 DHX8_HUMAN (1353-1741): 3.69e-48: 191: 11.03		RU17_HUMAN (8-237): 3.03e-40: 147: 30.00