Interactor 1: ATR (P38111)
Serine/threonine-protein kinase MEC1 (EC 2.7.11.1) (ATR homolog) (DNA-damage checkpoint kinase MEC1) (Mitosis entry checkpoint protein 1)
Gene: MEC1
Interactor 2: LCD1 (Q04377)
DNA damage checkpoint protein LCD1 (DNA damage checkpoint protein 2) (Lethal, checkpoint-defective, DNA damage-sensitive protein 1)
Gene: LCD1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.990 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10950868, 19028869, 19457865, 11359899, 11060031, 11154263, 29033322, 31340146, 37968396, 15755447, 15456903, 16148046, 26798134, 24586187, 17189191, 29191911, 33169019, 20489023 |
| Identification Methods | coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, affinity chromatography technology, two hybrid, enzymatic study, x-ray crystallography, tandem affinity purification, 3D electron microscopy |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FAT~LCD1 |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0005634 - nucleus GO:0006139 - nucleobase-containing compound metabolic process GO:0006281 - DNA repair GO:0006325 - chromatin organization and 2 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
