Interactor 1: ISU1 (Q03020)
Iron sulfur cluster assembly protein 1, mitochondrial (Iron sulfur cluster scaffold protein 1)
Gene: ISU1

Interactor 2: FRDA (Q07540)
Frataxin homolog, mitochondrial (EC 1.16.3.1) [Cleaved into: Frataxin homolog intermediate form]
Gene: YFH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 25228696, 12947415, 17186026, 18319250, 35026224, 19884169, 26941001, 28548666, 19491103, 20815377
Identification Methods pull down, affinity chromatography technology, x-ray crystallography, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Frataxin_Cyay~NifU_N
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006879 - intracellular iron ion homeostasis
GO:0008198 - ferrous iron binding
GO:0016226 - iron-sulfur cluster assembly
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 165
Sc

1 174
+ Hs
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024