HitPredict

Interactor 1: DCA13 (P33750)
Protein SOF1 (U3 small nucleolar RNA-associated protein SOF1) (U3 snoRNA-associated protein SOF1)
Gene: SOF1

Interactor 2: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	18467557
Identification Methods	protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 489 Sc			1 792
+	Sc
		673582 NLE1_YEAST (164-482): 1.06e-57: 200: 11.84		UBP10_YEAST (1-770): 1.83e-169: 510: 100.00
+	Hs
		1450206 DCA13_HUMAN (1-453): 2.33e-105: 322: 44.59		UBP36_HUMAN (252-786): 9.91e-83: 288: 18.89
+	Hs
		1131095 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		UBP10_HUMAN (5-734): 1.51e-111: 359: 16.10
+	Hs
		964952 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		UBP10_HUMAN (5-734): 1.51e-111: 359: 16.10
+	Hs
		1380218 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		UBP36_HUMAN (252-786): 9.91e-83: 288: 18.89
+	Mm
		1230662 TBL1X_MOUSE (89-485): 7.59e-67: 225: 12.78		UBP7_MOUSE (170-776): 1.12e-80: 282: 13.59
+	Hs
		288482 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		UBP2_HUMAN (98-738): 4.87e-79: 268: 15.22
+	Hs
		965296 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		UBP36_HUMAN (252-786): 9.91e-83: 288: 18.89
+	Hs
		965140 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		UBP7_HUMAN (160-776): 1.82e-81: 284: 13.38
+	Hs
		1450942 NLE1_HUMAN (288-486): 4.13e-35: 138: 14.15		UBP36_HUMAN (252-786): 9.91e-83: 288: 18.89
+	Hs
		1387566 SNR40_HUMAN (3-145): 2.89e-17: 84.9: 12.03		UBP42_HUMAN (339-765): 4.17e-94: 322: 20.99
+	Hs
		1387612 SNR40_HUMAN (3-145): 2.89e-17: 84.9: 12.03		UBP36_HUMAN (252-786): 9.91e-83: 288: 18.89
+	Hs
		1380269 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		UBP20_HUMAN (462-738): 2.64e-24: 111: 30.51
+	Hs
		261442 TBL1X_HUMAN (89-485): 1.24e-65: 223: 12.53		UBP44_HUMAN (454-732): 3.23e-15: 81.6: 24.68
+	Hs
		965228 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		UBP44_HUMAN (454-732): 3.23e-15: 81.6: 24.68
+	Hs
		1419997 TBL1R_HUMAN (7-152): 7.49e-18: 88: 14.46		UBP44_HUMAN (454-732): 3.23e-15: 81.6: 24.68
+	Dm
		1485083 FBXW7_DROME (289-466): 4.67e-22: 102: 14.62		UBP36_DROME (363-527): 8.21e-09: 61.2: 27.17