Interactor 1: RRP4 (P38792)
Exosome complex component RRP4 (Ribosomal RNA-processing protein 4)
Gene: RRP4

Interactor 2: RRP41 (P46948)
Exosome complex component SKI6 (Extracellular mutant protein 20) (Ribosomal RNA-processing protein 41) (Superkiller protein 6)
Gene: SKI6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 9390555, 17173052, 11805826, 16429126, 17391830, 18314965, 19707589, 37968396, 16729021
Identification Methods biochemical, tandem affinity purification, affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECR1_N~RNase_PH, ECR1_N~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 359
Sc

1 246
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+ Dm
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+ Hs
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+ Dm
+ Dm
+ Hs

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Last updated: 15 Jul 2024