HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 236
+	Hs
		957612 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		Q6PIA0_HUMAN (1-236): 3.8e-86: 257: 99.15
+	Hs
		957650 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00
+	Hs
		982291 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		BIRC8_HUMAN (1-236): 1.71e-86: 257: 100.00
+	Hs
		957642 UBE2K_HUMAN (1-97): 6.08e-34: 117: 100.00		BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47
+	Hs
		75521 B3KSH4_HUMAN (1-97): 3.95e-34: 114: 100.00		BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47
+	Hs
		982277 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		BIRC7_HUMAN (1-236): 7.02e-61: 194: 33.47
+	Hs
		982273 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		MIB2_HUMAN (37-234): 1.21e-28: 115: 19.34
+	Hs
		982264 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RFFL_HUMAN (64-236): 5.99e-24: 100: 17.78
+	At
		762751 UBC8_ARATH (1-52): 2.2e-30: 106: 38.46		RGLG3_ARATH (53-234): 4.97e-24: 100: 15.61
+	At
		762748 UBC8_ARATH (1-52): 2.2e-30: 106: 38.46		LUL3_ARATH (86-233): 1.32e-23: 99.3: 17.76
+	Hs
		982269 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		RNF34_HUMAN (161-236): 2.92e-23: 98: 36.84
+	Hs
		982263 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		MYLIP_HUMAN (166-235): 7.55e-21: 92.2: 35.71
+	Dm
		683044 UBCD1_DROME (1-51): 3.1e-30: 106: 39.22		DIAP1_DROME (4-84): 7.15e-19: 86.6: 32.93
+	Hs
		982180 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		957072 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		BIRC3_HUMAN (4-158): 6.1e-18: 84.3: 24.20
+	Hs
		982181 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		BIRC2_HUMAN (4-148): 3.09e-16: 79.3: 24.49
+	Hs
		957073 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		BIRC2_HUMAN (4-148): 3.09e-16: 79.3: 24.49
+	Hs
		982166 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07
+	Hs
		957062 UB2D3_HUMAN (1-51): 1.04e-29: 105: 35.29		XIAP_HUMAN (3-211): 1.27e-13: 71.6: 15.07
+	Hs
		982235 UB2D2_HUMAN (1-51): 8.37e-31: 107: 39.22		MIB1_HUMAN (158-233): 9.22e-12: 66: 25.00