HitPredict

Interactor 1: DMA1 (P38823)
E3 ubiquitin-protein ligase DMA1 (EC 2.3.2.27) (Checkpoint forkhead associated with RING domains-containing protein 1) (Defective in mitotic arrest protein 1) (RING-type E3 ubiquitin transferase DMA1)
Gene: DMA1

Interactor 2: DMA2 (P53924)
E3 ubiquitin-protein ligase DMA2 (EC 2.3.2.27) (Checkpoint forkhead associated with RING domains-containing protein 1) (Defective in mitotic arrest protein 2) (RING-type E3 ubiquitin transferase DMA2)
Gene: DMA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 11805837, 18202552, 37968396
Identification Methods anti tag coimmunoprecipitation, enzymatic study, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FHA~FHA
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0000151 - ubiquitin ligase complex
GO:0000921 - septin ring assembly
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
and 16 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 416
Sc

1 522
+ Sc
+ Sc
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024