Interactor 1: SET1 (P38827)
Histone-lysine N-methyltransferase, H3 lysine-4 specific (EC 2.1.1.354) (COMPASS component SET1) (Lysine N-methyltransferase 2) (SET domain-containing protein 1)
Gene: SET1

Interactor 2: SPP1 (Q03012)
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)
Gene: SPP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 11752412, 11742990, 23453808, 11687631, 16554755, 16429126, 26527276, 16921172, 29444071, 30479350, 30325428, 19713935, 37774018, 37968396, 22158900, 32358498, 23160953, 21179020
Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, biochemical, two hybrid, x-ray crystallography, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0031509 - subtelomeric heterochromatin formation
GO:0048188 - Set1C/COMPASS complex
GO:1903341 - regulation of meiotic DNA double-strand break formation
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1080
Sc

1 353
+ Sp
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
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Last updated: 15 Jul 2024