HitPredict

Interactor 1: ATG7 (P38862)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (Cytoplasm to vacuole targeting protein 2)
Gene: ATG7

Interactor 2: ATG7 (P38862)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (Cytoplasm to vacuole targeting protein 2)
Gene: ATG7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 12965207, 11139573, 27477278, 21193819, 22056771
Identification Methods two hybrid, affinity chromatography technology, pull down, molecular sieving, light scattering, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG7_N~ATG7_N, ThiF~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 13 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 630
Sc

1 630
+ Hs
+ Mm
+ Zm
+ Sc
+ Hs
+ Hs
+ Ec
+ Sc
+ Oc
+ Hs
+ Sc
+ Hs
+ Sp
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024