HitPredict

Interactor 1: YKA7 (P34258)
Uncharacterized protein B0303.7
Gene: B0303.7

Interactor 2: Q95PW9 (Q95PW9)
NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family
Gene: nck-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	SH2~SH3_1, SH3_1~SH3_1, SH3_1~SH3_2
Common GO terms	GO:0016477 - cell migration
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 493 Ce			1 395
+	Hs
		222014 NCK1_HUMAN (130-350): 1.97e-30: 123: 17.83		NCK2_HUMAN (2-393): 1.76e-85: 266: 37.82
+	Hs
		221982 NCK2_HUMAN (126-351): 8.59e-29: 119: 18.72		NCK2_HUMAN (2-393): 1.76e-85: 266: 37.82
+	Hs
		593897 NCK1_HUMAN (130-350): 1.97e-30: 123: 17.83		NCK1_HUMAN (2-394): 4.11e-81: 255: 38.54
+	Mm
		237077 SRBS1_MOUSE (175-328): 8.49e-19: 92.2: 19.23		NCK2_MOUSE (2-393): 2.91e-84: 263: 38.33
+	Hs
		440171 SH3K1_HUMAN (362-493): 1.95e-15: 81.1: 18.71		LCK_HUMAN (176-378): 5.22e-55: 190: 30.05
+	Hs
		1154182 ITSN1_HUMAN (26-493): 1.79e-29: 124: 11.00		ITSN2_HUMAN (8-285): 3.76e-34: 136: 19.61
+	Hs
		1154087 ITSN1_HUMAN (26-493): 1.79e-29: 124: 11.00		ITSN1_HUMAN (5-269): 4.52e-32: 130: 14.77
+	Hs
		1453434 ITSN2_HUMAN (185-439): 1.01e-25: 113: 17.69		ITSN2_HUMAN (8-285): 3.76e-34: 136: 19.61
+	Hs
		593961 NCK1_HUMAN (130-350): 1.97e-30: 123: 17.83		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Hs
		699767 ITSN1_HUMAN (26-493): 1.79e-29: 124: 11.00		P85A_HUMAN (272-393): 2.21e-20: 95.2: 20.00
+	Hs
		593920 NCK1_HUMAN (130-350): 1.97e-30: 123: 17.83		P85A_HUMAN (272-393): 2.21e-20: 95.2: 20.00
+	Hs
		987684 SH319_HUMAN (162-329): 1.15e-21: 100: 22.02		GRB2_HUMAN (5-175): 2.31e-28: 112: 20.37
+	Mm
		813529 NCK1_MOUSE (130-350): 1.02e-30: 124: 16.96		FYN_MOUSE (6-108): 2.85e-17: 85.6: 19.05
+	Hs
		440576 ITSN1_HUMAN (26-493): 1.79e-29: 124: 11.00		FYN_HUMAN (6-108): 2.98e-17: 85.2: 19.05
+	Hs
		440340 NCK1_HUMAN (130-350): 1.97e-30: 123: 17.83		FYN_HUMAN (6-108): 2.98e-17: 85.2: 19.05
+	Ce
		1457938 Q9U2T9_CAEEL (74-491): 1.5e-26: 116: 12.22		Q9U2T9_CAEEL (2-58): 1.08e-10: 65.5: 26.67
+	Ce
		234031 SEM5_CAEEL (255-335): 1.28e-21: 95.3: 25.93		SRC2_CAEEL (6-125): 1.55e-15: 80.2: 15.57
+	Hs
		440667 SH3K1_HUMAN (362-493): 1.95e-15: 81.1: 18.71		FYN_HUMAN (6-108): 2.98e-17: 85.2: 19.05